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Digital Library of the
European Council for Modelling and Simulation |
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Title: |
Modelling A Peroxidase-Based
Fluorescent Biosensor |
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Authors: |
Evelina Gaidamauskaitė, Romas
Baronas |
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Published in:
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ECMS
2008 Proceedings Edited
by: Loucas S. Louca, Yiorgos Chrysanthou, Zuzana Oplatkova, Khalid Al-Begain ISBN:
978-0-9553018-6-5 Doi: 10.7148/2008 22nd
European Conference on Modelling and Simulation, Nicosia, June
3-6, 2008 |
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Citation
format: |
Gaidamauskaite, E., & Baronas,
R. (2008). Modelling A Peroxidase-Based
Fluorescent Biosensor. ECMS 2008 Proceedings edited by: L. S. Louca, Y. Chrysanthou, Z. Oplatkova, K. Al-Begain
(pp. 152-156). European Council for Modeling and Simulation. doi:10.7148/2008-0152. |
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DOI: |
http://dx.doi.org/10.7148/2008-0152 |
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Abstract: |
The
paper presents a one-dimensional-in-space mathem- atical model of a peroxidase-based
fluorescent biosensor. The mathematical model is based on a system of non-
linear reaction diffusion equations. The problem was solved numerically using
finite difference technique. The model was used to study the effect of
biosensor paramet- ers,
namely the thickness of the enzyme layer and the outer substrate
concentration, on the response of the bi- osensor
and it’s sensitivity. The performed calculations showed a complex influence
of the substrate and hydro- gen peroxide concentrations. |
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