Digital Library of the European Council for Modelling and Simulation

Title:	Modeling And Simulation Of Porous Multi Layer Microbioreactors
Authors:	Linas Petkevicius, Romas Baronas
Published in:	(2019). ECMS 2019 Proceedings Edited by: Mauro Iacono, Francesco Palmieri, Marco Gribaudo, Massimo Ficco, European Council for Modeling and Simulation. DOI: http://doi.org/10.7148/2019 ISSN: 2522-2422 (ONLINE) ISSN: 2522-2414 (PRINT) ISSN: 2522-2430 (CD-ROM) 33rd International ECMS Conference on Modelling and Simulation, Caserta, Italy, June 11^th – June 14^th, 2019
Citation format:	Linas Petkevicius, Romas Baronas (2019). Modeling And Simulation Of Porous Multi Layer Microbioreactors, ECMS 2019 Proceedings Edited by: Mauro Iacono, Francesco Palmieri, Marco Gribaudo, Massimo Ficco European Council for Modeling and Simulation. doi: 10.7148/2019-0190
DOI:	https://doi.org/10.7148/2019-0190
Abstract:	The paper presents a non-linear mathematical model of the batch stirred tank reactor with spherical catalyst porous particles as microreactors. The mathematical model when microreactors are covered with an outer protective layer is investigated. The model is based on a system of reaction-di˙usion equations, contain-ing a non-linear term related to the Michaelis-Menten kinetics, and involves four regions: the enzyme mi-croreactor where the enzyme reaction as well as mass transport by di˙usion take place, a protective layer and the Nernst layer with di˙usion limiting regions, where only the mass transport by di˙usion takes place, and a convective region, where the analyte concentration is maintained constant. The influence on process du-ration and process eÿciency of the di˙usion modulus, the Biot number and inverse adsorption capacity has been numerically investigated. The simulation results showed that protective layer allow to control product emission as well as allow easier control the target con-centration. The digital simulation was carried out using the finite di˙erence technique.
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